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The command line parameters (including the path to the correct version of Progress OpenEdge client executable (prowin32.exe or prowin.exe), the ini file, pf files connecting the databases etc. need to be specified in the Business Entity Designer options on the "Launcher" tab. The launcher will use those command line parameters to start the Business Entity Designer with the right configuration. Without this setting the launcher will not be able to start the Business Entity Designer.
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